i. Symptoms of Benign Prostatic Hyperplasia
ii. Diagnosis of Benign Prostatic Hyperplasia
iii. Treatment of Benign Prostatic Hyperplasia
iv. European Market for Benign Prostatic Drugs, Devices, and Therapies
v. Methodology
Exhibit ES-1: The Prostate and Urine Flow
Exhibit ES-2: Commonly Prescribed Drugs for Benign Prostatic Hyperplasia
Exhibit ES-3: Europe, Benign Prostatic Hyperplasia Treatment Products, Combined Market Forecast, 2006-2011
1. EUROPEAN HEALTHCARE MARKETS
1.1 The European Union
1.1.1 A Common Currency
1.1.2 Regulatory Policies
1.1.3 Reimbursement
1.1.4 Healthcare Spending
1.2 Selected European National Healthcare Profiles
1.2.1 France
1.2.1.1 Healthcare Organization and Reform
1.2.1.2 Hospital Services
1.2.1.3 Medical Device Reimbursement
1.2.2 Germany
1.2.2.1 Healthcare Organization and Reform
1.2.2.2 Hospital Services
1.2.2.3 Medical Device Reimbursement
1.2.3 Italy
1.2.3.1 Healthcare Organization and Reform
1.2.3.2 Hospital Services
1.2.3.3 Medical Device Reimbursement
1.2.4 Spain
1.2.4.1 Healthcare Organization and Reform
1.2.4.2 Hospital Services
1.2.4.3 Medical Device Reimbursement
1.2.5 United Kingdom
1.2.5.1 Healthcare Organization and Reform
1.2.5.2 Hospital Services
1.2.5.3 Medical Device Reimbursement
1.2.6 Benelux
1.2.6.1 Healthcare Organization and Reform
1.2.6.1.1 Belgium
1.2.6.1.2 Luxembourg
1.2.6.1.3 The Netherlands
1.2.6.2 Hospital Services
1.2.6.3 Medical Device Reimbursement
Exhibit 1-1: European Union, Medical Devices Risk Classification System
Exhibit 1-2: 2007, Europe, Population Statistics, Selected Countries
Exhibit 1-3: France, Selected National Healthcare Statistics
Exhibit 1-4: Germany, Selected National Healthcare Statistics
Exhibit 1-5: Italy, Selected National Healthcare Statistics
Exhibit 1-6: Spain, Selected National Healthcare Statistics
Exhibit 1-7: United Kingdom, Selected National Healthcare Statistics
Exhibit 1-8: Belgium, Selected National Healthcare Statistics
Exhibit 1-9: Luxembourg, Selected National Healthcare Statistics
Exhibit 1-10: The Netherlands, Selected National Healthcare Statistics
2. CLINICAL OVERVIEW OF BENIGN PROSTATIC HYPERPLASIA
2.1 Causes
2.2 Symptoms
2.3 Diagnosis
2.4 Treatment
2.4.1 Prescription Drugs
2.4.2 Minimally Invasive Therapy
2.4.3 Surgery
2.4.4 Stents
Exhibit 2-1: The Prostate and Urine Flow
Exhibit 2-2: Commonly Prescribed Drugs for Benign Prostatic Hyperplasia
3. BENIGN PROSTATIC HYPERPLASIA THERAPY PRODUCTS MARKET
3.1 Drug Therapy
3.1.1 Alpha Blockers
3.1.1.1 Cardura/Cardura XL: Pfizer
3.1.1.2 Flomax: Astellas Pharma
3.1.1.3 Hytrin: Abbott Laboratories
3.1.1.4 Xatral: sanofi-aventis
3.1.1.5 Others
3.1.2 5 Alpha-Reductase Inhibitors
3.1.2.1 Avodart: GlaxoSmithKline
3.1.2.2 Proscar: Merck
3.1.3 Emerging Drugs and Investigational Drug Combinations
3.1.3.1 Cetrorelix and Ozarelix: AEterna Zentaris
3.1.3.2 Cialis: Eli Lilly
3.1.3.3 Degarelix: Ferring Pharmaceuticals
3.1.3.4 Dutasteride/Tamsulosin Combination: GlaxoSmithKline
3.1.3.5 Elocalcitol: BioXell
3.1.3.6 Etonogestrel: Organon/Schering-Plough
3.1.3.7 Levitra: Bayer
3.1.3.8 Naftopidil: Asahi Kasei
3.1.3.9 NX-1207: Nymox Pharmaceutical
3.1.3.10 Silodosin: Kissei Pharmaceutical
3.1.3.11 UK-369003: Pfizer
3.1.3.12 Zydena: Dong-A Pharmaceutical
3.1.3.13 Suspended Trials
3.1.4 Alternative Treatments
3.1.4.1 Aspirin
3.1.4.2 Beta Sitosterol
3.1.4.3 Botulinum Toxin Type A
3.1.4.4 Lycopene
3.1.4.5 Pomegranate
3.1.4.6 Pygeum Africanum
3.1.4.7 Saw Palmetto
3.2 Minimally Invasive Therapy
3.2.1 Microwave Thermotherapy
3.2.1.1 CoreTherm System: ProstaLund
3.2.1.2 Prolieve Thermodilatation System: Boston Scientific
3.2.1.3 Prostatron and Targis Cooled ThermoTherapy: Urologix
3.2.1.4 TherMatrx Office Thermo Therapy: American Medical Systems
3.2.2 Transurethral Needle Ablation/Radiofrequency Therapy
3.2.3 Holmium Laser Ablation/Enucleation of the Prostate
3.2.3.1 VersaPulse PowerSuite: Lumenis
3.2.4 Interstitial Laser Coagulation
3.2.5 Photoselective Vaporization of the Prostate
3.2.5.1 GreenLight Laser Therapy: American Medical Systems
3.2.6 Water-Induced Thermotherapy: Gyrus ACMI/Olympus
3.2.7 Other Energy-Based Technologies
3.3 Prostatic Stents
3.3.1 The Spanner Prostatic Stent: AbbeyMoor Medical
3.3.2 CoreFlow Soft Stent: ProstaLund
3.3.3 ProstaPlant Prostate Stent: ProstaPlant Urology Systems
3.3.4 UroLume Urethral Stent: American Medical Systems
3.3.5 URO-Stent: Global Pacific Minerals
3.4 Surgical Treatment
3.4.1 Plasmakinetic Transurethral Resection of the Prostate: Gyrus ACMI/Olympus
3.5 Market Analysis
3.5.1 Drug Therapy
3.5.1.1 Patient Volumes Forecast
3.5.1.2 Market Forecast
3.5.1.3 Competitive Analysis
3.5.2 Minimally Invasive Therapy
3.5.2.1 Procedure Volumes Forecast
3.5.2.2 Market Analysis
3.5.2.3 Competitive Analysis
3.5.3 Combined Market Forecast
Exhibit 3-1: 2008, Selected Benign Prostatic Hyperplasia Drugs
Exhibit 3-2: 2008, Selected Emerging Benign Prostatic Hyperplasia Drugs
Exhibit 3-3: Advantages and Disadvantages of Minimally Invasive Therapy
Exhibit 3-4: 2008, Selected Minimally Invasive Benign Prostatic Hyperplasia Therapy Systems
Exhibit 3-5: ProstaLund's CoreTherm System
Exhibit 3-6: The Schelin Catheter
Exhibit 3-7: The Prostiva Radiofrequency Therapy System
Exhibit 3-8: Benefits of the Prostiva Radiofrequency Therapy System
Exhibit 3-9: The VersaPulse PowerSuite Laser System, Holmium Laser Ablation of the Prostate
Exhibit 3-10: The GreenLight High Performance System
Exhibit 3-11: Benefits of the GreenLight Laser Therapy System
Exhibit 3-12: The Spanner Prostatic Stent
Exhibit 3-13: The CoreFlow Soft Stent
Exhibit 3-14: Benefits of the UroLume Urethral Stent
Exhibit 3-15: Advantages of Plasmakinetic Transurethral Resection of the Prostate
Exhibit 3-16: Europe, Benign Prostatic Hyperplasia Drug Therapy, Patient Volumes Forecast, 2006-2011
Exhibit 3-17: Europe, Benign Prostatic Hyperplasia Drug Therapy, Market Forecast, 2006-2011
Exhibit 3-18: 2006, Europe, Benign Prostatic Hyperplasia Drug Therapy Market, Share by Supplier
Exhibit 3-19: 2007, Europe, Benign Prostatic Hyperplasia Drug Therapy Market, Share by Supplier
Exhibit 3-20: Europe, Minimally Invasive Benign Prostatic Hyperplasia Therapy, Procedure Volumes Forecast, 2006-2011
Exhibit 3-21: Europe, Minimally Invasive Benign Prostatic Hyperplasia Therapy Systems, Market Forecast, 2006-2011
Exhibit 3-22: 2006, Europe, Minimally Invasive Benign Prostatic Hyperplasia Therapy Systems Market, Share by Supplier
Exhibit 3-23: 2007, Europe, Minimally Invasive Benign Prostatic Hyperplasia Therapy Systems Market, Share by Supplier
Exhibit 3-24: Europe, Benign Prostatic Hyperplasia Treatment Products, Combined Market Forecast, 2006-2011
4. COMPANY PROFILES
4.1 AbbeyMoor Medical, Inc.
4.2 Abbott Laboratories
4.3 AEterna Zentaris, Inc.
4.4 American Medical Systems Holdings, Inc.
4.5 Astellas Pharma, Inc.
4.6 Boehringer Ingelheim GmbH
4.7 Boston Scientific Corporation
4.8 GlaxoSmithKline PLC
4.9 Gyrus ACMI, Inc./Olympus Corporation
4.10 Kissei Pharmaceutical Company LTD
4.11 Lumenis LTD
4.12 Medtronic, Inc.
4.13 Merck & Company, Inc.
4.14 Nymox Pharmaceutical Corporation
4.15 Pfizer, Inc.
4.16 ProstaLund Operations AB
4.17 sanofi-aventis SA
4.18 Spectrum Pharmaceuticals, Inc.
4.19 Urologix, Inc.
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