This dynamic new report from Medtech Insight includes analyses of products, current/forecast markets, competitors, and opportunities in the European market for nonfusion spinal technologies for the treatment of degenerative disc disease. Product areas covered by the scope of this report include artificial discs, dynamic stabilization systems (facet replacements, interspinous process spacers, and pedicle screws), kyphoplasty and vertebroplasty systems, nucleus replacements, and percutaneous intradiscal electrotherapy and plasma disc decompression devices.
During the forecast period covered by this report, the combined European market for spinal motion-preserving devices is projected to increase at a compound annual rate of 5.4%, reaching an estimated $524.8 million in the year 2017. The segment that is projected to experience the greatest growth is represented by sales of artificial discs, followed by dynamic stabilization systems and vertebral compression fracture repair products, with disc altering systems experiencing modest growth over the next half-decade. The European market for nucleus replacement devices for degenerative disc disease has declined in recent years.
EXECUTIVE SUMMARY i. Artificial Discs ii. Dynamic Stabilization iii. Vertebral Compression Fracture Products iv. Disc Altering Products v. Methodology 1. CLINICAL OVERVIEW OF DEGENERATIVE SPINAL DISORDERS 1.1 Anatomy of the Human Spine 1.1.1 Vertebrae 1.1.2 Intervertebral Discs 1.1.3 Spinal Cord 1.2 Bone Physiology and Remodeling 1.3 Degenerative Disorders 1.3.1 Degenerative Disc Disease 1.3.2 Herniated Disc 1.3.3 Spinal Stenosis 1.3.4 Spondylosis 1.3.5 Spondylolisthesis 1.3.6 Osteoporosis 1.3.7 Rheumatoid Arthritis 1.3.8 Paget's Disease Exhibit 1-1: The Human Spine Exhibit 1-2: A Segment of the Spinal Column Exhibit 1-3: A Simple Illustrated Diagram of a Spinal Disc Exhibit 1-4: Common Degenerative Spinal Disorders Exhibit 1-5: Stages of a Disc Herniation Exhibit 1-6: A Healthy Cervical Spine in Comparison to Spinal Stenosis and Herniation Exhibit 1-7: A Simple Illustrated Diagram of Spondylolisthesis in the Spine Exhibit 1-8: A Simple Illustrated Diagram of a Vertebral Compression Fracture 2. TOTAL DISC REPLACEMENT 2.1 Materials and Designs 2.2 Artificial Cervical Discs 2.2.1 Selected Clinical Evidence Regarding Artificial Cervical Discs 22.214.171.124 The Bryan Disc 126.96.36.199 The Mobi-C Disc 188.8.131.52 The Prestige Disc 184.108.40.206 The ProDisc-C Disc 220.127.116.11 The SECURE-C Disc 2.3 Artificial Lumbar Discs 2.3.1 Products 18.104.22.168 AxioMed Spine 22.214.171.124 B. Braun Melsungen 126.96.36.199 DePuy Synthes/Johnson & Johnson 188.8.131.52 Globus Medical 184.108.40.206 LDR 220.127.116.11 Ranier Technology 18.104.22.168 Spinal Kinetics 2.3.2 Pipeline Products No Longer Under Development 2.4 Market Analysis 2.4.1 Artificial Cervical Discs 2.4.2 Artificial Lumbar Discs 2.5 Competitive Analysis 2.5.1 Artificial Cervical Discs 2.5.2 Artificial Lumbar Discs Exhibit 2-1: Differentiating Features of Artificial Disc Designs Exhibit 2-2: Important Mechanical Properties of Artificial Discs Exhibit 2-3: 2014, Selected Artificial Cervical Discs Exhibit 2-4: 2014, Selected Artificial Lumbar Discs Exhibit 2-5: Comparison of Second-Generation Artificial Lumbar Disc Technology with First-Generation Technology Exhibit 2-6: Europe, Artificial Discs, Combined Market Forecast, by Country, 2012-2017 Exhibit 2-7: Europe, Artificial Cervical Discs, Market Forecast, by Country, 2012-2017 Exhibit 2-8: Europe, Artificial Lumbar Discs, Market Forecast, by Country, 2012-2017 Exhibit 2-9: 2012, Europe, Artificial Cervical Discs Market, Share by Supplier Exhibit 2-10: 2012, Europe, Artificial Lumbar Discs Market, Share by Supplier 3. DISC NUCLEUS REPLACEMENT TECHNOLOGIES 3.1 Product Development Programs 3.2 Abandoned Pipeline Products 3.3 Market Analysis Exhibit 3-1: The Prosthetic Disc Nucleus Exhibit 3-2: The NeuDisc Exhibit 3-3: The Percutaneous Nucleus Replacement 4. DYNAMIC STABILIZATION DEVICES 4.1 Types of Devices 4.1.1 Interspinous Process Spacers 4.1.2 Pedicle Screw Dynamic Stabilization Systems 4.1.3 Facet Replacements 4.2 Indications 4.3 Products 4.3.1 Interspinous Process Spacers 22.214.171.124 Scient'x/Alphatec Spine 126.96.36.199 Biomet 188.8.131.52 DePuy Synthes/Johnson & Johnson 184.108.40.206 Globus Medical 220.127.116.11 Medtronic 18.104.22.168 Paradigm Spine 22.214.171.124 Simpirica Spine 126.96.36.199 Vertiflex 188.8.131.52 Zimmer 4.3.2 Pedicle Screw-Based Dynamic Stabilization Systems 184.108.40.206 DePuy Synthes/Johnson & Johnson 220.127.116.11 Globus Medical 18.104.22.168 Mekanika 22.214.171.124 Paradigm Spine 126.96.36.199 Scient'x/Alphatec Spine 188.8.131.52 SpineVision 184.108.40.206 Zimmer 4.3.3 Facet Replacement 220.127.116.11 Globus Medical 18.104.22.168 Premia Spine 22.214.171.124 Zyga Technology 4.4 Market Analysis 4.5 Competitive Analysis Exhibit 4-1: Anatomic Changes Achieved by Dynamic Stabilization Devices Exhibit 4-2: 2014, Selected Interspinous Process Spacers Exhibit 4-3: 2014, Selected Pedicle Screw-Based Dynamic Stabilization Systems Exhibit 4-4: 2014, Selected Facet Replacement Products Exhibit 4-5: Europe, Dynamic Stabilization Products, Market Forecast, By Country, 2012-2017 Exhibit 4-6: 2012, Dynamic Stabilization Products Market, Share by Supplier 5. VERTEBRAL COMPRESSION FRACTURE PRODUCTS 5.1 Vertebroplasty 5.1.1 Polymethylmethacrylate Alternatives 5.1.2 Products 5.2 Kyphoplasty/Balloon-Assisted Vertebral Augmentation Systems 5.2.1 Products 5.3 Other Vertebral Augmentation Systems 5.4 Market Analysis 5.4.1 Vertebroplasty 5.4.2 Kyphoplasty and Balloon-Assisted Vertebral Augmentation Systems 5.5 Competitive Analysis 5.5.1 Vertebroplasty 5.5.2 Kyphoplasty and Balloon-Assisted Vertebral Augmentation Systems Exhibit 5-1: The Vertebroplasty Procedure Exhibit 5-2: Vertebroplasty Indications and Contraindications Exhibit 5-3: 2014, Selected Vertebroplasty Systems Exhibit 5-4: The Balloon Kyphoplasty Procedure Exhibit 5-5: Kyphoplasty, Selected Advantages and Disadvantages Exhibit 5-6: 2014, Selected Kyphoplasty and Balloon-Assisted Vertebral Augmentation Systems Exhibit 5-7: 2014, Selected Alternative Vertebral Augmentation Systems Exhibit 5-8: Europe, Vertebroplasty Systems, Market Forecast, by Country, 2012-2017 Exhibit 5-9: Europe, Kyphoplasty and Balloon-Assisted Vertebral Augmentation Systems, Market Forecast, by Country, 2012-2017 Exhibit 5-10: 2012, Europe, Vertebroplasty Systems Market, Share by Supplier Exhibit 5-11: 2012, Europe, Kyphoplasty and Balloon-Assisted Vertebral Augmentation Systems Market, Share by Supplier 6. DISC ALTERING PRODUCTS 6.1 Intradiscal Electrothermal Therapy 6.1.1 Clinical Evidence 6.1.2 Practice Guidelines 6.1.3 Products 6.2 Plasma Disc Decompression 6.2.1 Clinical Evidence 6.2.2 Practice Guidelines 6.3 Emerging Technology 6.4 Market Analysis 6.5 Competitive Analysis Exhibit 6-1: The SpineCath Intradiscal Catheter Exhibit 6-2: The Plasma Disc Decompression Procedure Exhibit 6-3: Europe, Disc Altering Products, Market Forecast, 2012-2017 Exhibit 6-4: Europe, Disc Altering Products, Market Forecast, by Country, 2012-2017 Exhibit 6-5: 2012, Europe, Disc Altering Products Market, Share by Supplier APPENDIX: COMPANY LISTING