U.S. MARKETS FOR INTERVENTIONAL CARDIOLOGY PRODUCTS

371 Pages | 99 Exhibits | 2005 Analysis | Forecasts Through 2009 Product Family: Market Reports




OVERVIEW:
More adults in the U.S. die from cardiovascular diseases/disorders than from any other cause. Nationwide, approximately 70.1 million people have at least one cardiovascular condition; these diseases/disorders kill nearly 2,600 people in the U.S. each day, and result in direct and indirect costs that exceed $393.5 billion annually.

In 2004, nearly 5.2 million diagnostic and therapeutic interventional cardiology procedures were performed in the U.S. These procedures generated more than $4.9 billion in corresponding product sales, with sales of devices used in therapeutic procedures accounting for approximately 92.2% of the total. Growing at a compound annual rate of 5.2%, interventional cardiology product sales are expected to reach an estimated $6.4 billion in the year 2009.

This dynamic report from Medtech Insight includes analyses of products and technologies, current and forecast markets, competitors, and opportunities in the U.S. market for interventional cardiology products.

Covered topics in this report include chronic total occlusion crossing systems; coronary angiography devices; coronary stents/stenting systems; embolic protection systems; endovascular brachytherapy systems; functional angiometry wires; intravascular and intracardiac ultrasound systems; laser atherectomy systems; mechanical atherectomy systems; mechanical thrombectomy systems; percutaneous balloon valvuloplasty systems; percutaneous transluminal coronary angioplasty devices such as balloon catheters, guiding catheters, guidewires, introducers/sheaths, and inflation devices; transcatheter septal defect repair systems; and vascular access site closure systems.

TABLE OF CONTENTS:

EXECUTIVE SUMMARY

i. Overview of Selected Cardiovascular Diseases/Disorders

a. Atherosclerosis

b. Myocardial Infarction

c. Congestive Heart Failure

d. Heart Valve Disorders

e. Congenital Cardiovascular Defects

ii. Interventional Cardiology Procedure Volumes and Products Markets

a. Diagnostic Interventional Cardiology

i. Coronary Angiography Devices

ii. Intravascular Ultrasound Systems

iii. Functional Angiometry Wires

iv. Intracardiac Ultrasound Systems

b. Therapeutic Interventional Cardiology

i. Percutaneous Transluminal Coronary Angioplasty Devices

ii. Coronary Stents/Stenting Systems

iii. Mechanical Thrombectomy Systems

iv. Endovascular Brachytherapy Systems

v. Mechanical Atherectomy Systems

vi. Laser Atherectomy Systems

vii. Chronic Total Occlusion Crossing Systems

viii. Embolic Protection Systems

ix. Percutaneous Balloon Valvuloplasty Systems

x. Transcatheter Septal Defect Repair Systems

xi. Vascular Access Site Closure Systems

iii. Methodology

Exhibit ES-1: Incidence and Prevalence Statistics for Selected Cardiovascular Diseases/Disorders, 2004 and 2009

Exhibit ES-2: Diagnostic and Therapeutic Interventional Cardiology, Procedure Volumes Forecast, 2004-2009

Exhibit ES-3: Diagnostic and Therapeutic Interventional Cardiology Products, Market Forecast, 2004-2009

Exhibit ES-4: Diagnostic Interventional Cardiology, Procedure Volumes Forecast, 2004-2009

Exhibit ES-5: Diagnostic Interventional Cardiology Products, Market Forecast, 2004-2009

Exhibit ES-6: Coronary Angiography Devices, Market Forecast, 2004-2009

Exhibit ES-7: Coronary Intravascular Ultrasound Catheter Products, Market Forecast, 2004-2009

Exhibit ES-8: Functional Angiometry Wires, Market Forecast, 2004-2009

Exhibit ES-9: Intracardiac Ultrasound Catheter Products, Market Forecast, 2004-2009

Exhibit ES-10: Therapeutic Interventional Cardiology, Procedure Volumes Forecast, 2004-2009

Exhibit ES-11: Therapeutic Interventional Cardiology Products, Market Forecast, 2004-2009

Exhibit ES-12: Percutaneous Transluminal Coronary Angioplasty Devices, Market Forecast, 2004-2009

Exhibit ES-13: Coronary Stents/Stenting Systems, Market Forecast, 2004-2009

Exhibit ES-14: Coronary Mechanical Thrombectomy Devices, Market Forecast, 2004-2009

Exhibit ES-15: Coronary Endovascular Brachytherapy Products, Market Forecast, 2004-2009

Exhibit ES-16: Coronary Mechanical Atherectomy Systems, Market Forecast, 2004-2009

Exhibit ES-17: Coronary Laser Atherectomy Devices, Market Forecast, 2004-2009

Exhibit ES-18: Coronary Mechanical Chronic Total Occlusion Crossing Systems, Market Forecast, 2004-2009

Exhibit ES-19: Coronary Embolic Protection Systems, Market Forecast, 2004-2009

Exhibit ES-20: Percutaneous Balloon Valvuloplasty Systems, Market Forecast, 2004-2009

Exhibit ES-21: Transcatheter Septal Defect Repair Devices, Market Forecast, 2004-2009

Exhibit ES-22: Vascular Access Site Closure Systems, Market Forecast, 2004-2009

1. OVERVIEW OF SELECTED CARDIOVASCULAR DISEASES/DISORDERS

1.1 Anatomy and Physiology of the Heart

1.2 Vascular Diseases/Disorders

1.2.1 Atherosclerosis

1.2.2 Coronary Heart Disease

1.2.2.1 Angina Pectoris

1.2.2.2 Myocardial Infarction

1.3 Myocardial Diseases/Disorders

1.3.1 Congestive Heart Failure

1.3.2 Heart Valve Disorders

1.3.3 Congenital Cardiovascular Defects

1.3.4 Rheumatic Fever/Rheumatic Heart Disease

Exhibit 1-1: Standard Angina Pectoris Classification

Exhibit 1-2: Incidence and Prevalence Statistics for Selected Vascular Diseases/Disorders, 2004 and 2009

Exhibit 1-3: 2004, Total Mention Mortality Figures for Selected Vascular Diseases/Disorders

Exhibit 1-4: New York Heart Association Classification System for Congestive Heart Failure

Exhibit 1-5: Clinical Characteristics of the Most Prevalent Congenital Heart Defects

Exhibit 1-6: Incidence and Prevalence Statistics for Selected Myocardial Diseases/Disorders, 2004 and 2009

Exhibit 1-7: 2004, Total Mention Mortality Figures for Selected Myocardial Diseases/Disorders

2. INTERVENTIONAL CARDIOLOGY PROCEDURES

2.1 Diagnostic Procedures

2.1.1 Coronary Angiography

2.1.1.1 Indications

2.1.1.2 Procedure Volumes Forecast

2.1.2 Intravascular Ultrasound

2.1.2.1 Indications

2.1.2.2 Procedure Volumes Forecast

2.1.3 Functional Angiometry

2.1.3.1 Indications

2.1.3.2 Procedure Volumes Forecast

2.1 4 Intracoronary Angioscopy

2.1.4.1 Indications

2.1.4 2 Procedure Volumes

2.1.5 Intracardiac Ultrasound

2.1.5.1 Indications

2.1.5.2 Procedure Volumes Forecast

2.2 Therapeutic Procedures

2.2.1 Percutaneous Transluminal Coronary Angioplasty

2.2.1.1 Indications

2.2.1.2 Procedure Volumes Forecast

2.2.2 Coronary Stenting

2.2.2.1 Characteristics of Coronary Stents

2.2.2.1.1 Coronary Stent Materials, Coatings/Surfaces, and Configurations

2.2.2.1.2 Coronary Stent Delivery and Deployment

2.2.2.1.3 Indications

2.2.2.1.4 Complications

2.2.2.1.5 Coronary Stenting, Caseload Forecast

2.2.2.2 Bare-Metal Stenting versus Drug-Eluting Stenting

2.2.2.2.1 Bare-Metal Stents, Placement Forecast

2.2.2.2.2 Anti-Restenosis Drugs Used in Drug-Eluting Stents

2.2.2.2.3 Anti-Restenosis Drug Delivery Using Drug-Eluting Stents

2.2.2.2.4 Clinical Trials

2.2.2.2.5 Drug-Eluting Stents, Placement Forecast

2.2.2.3 Bare-Metal Stenting Plus Adjuvant Systemic Anti-Restenosis Drug Therapy

2.2.2.3.1 Indications

2.2.2.3.2 Bare-Metal Stenting Plus Adjuvant Systemic Anti-Restenosis Drug Therapy, Caseload Forecast

2.2.3 Mechanical Thrombectomy

2.2.3.1 Indications

2.2.3.2 Procedure Volumes Forecast

2.2.4 Endovascular Brachytherapy

2.2.4.1 Indications

2.2.4.2 Procedure Volumes Forecast

2.2.5 Mechanical Atherectomy

2.2.5.1 Mechanical Atherectomy Techniques

2.2.5.1.1 Directional Atherectomy

2.2.5.1.2 Rotational Atherectomy

2.2.5.1.3 Extraction Atherectomy

2.2.5.2 Indications

2.2.5.3 Procedure Volumes Forecast

2.2.6 Laser Atherectomy

2.2.6.1 Indications

2.2.6.2 Procedure Volumes Forecast

2.2.7 Chronic Total Occlusion Crossing

2.2.7.1 Current and Emerging Chronic Total Occlusion Techniques

2.2.7.2 Procedure Volumes Forecast

2.2.8 Embolic Protection

2.2.8.1 Embolic Protection Technologies

2.2.8.1.1 Distal Filtration

2.2.8.1.2 Distal Balloon Occlusion

2.2.8.1.3 Proximal Balloon Occlusion

2.2.8.2 Utilization Trends

2.2.8.3 Procedure Volumes Forecast

2.2.9 Percutaneous Balloon Valvuloplasty

2.2.9.1 Indications

2.2.9.2 Procedure Volumes Forecast

2.2.10 Transcatheter Septal Defect Repair

2.2.10.1 Types of Repair

2.2.10.1.1 Patent Ductus Arteriosus Repair

2.2.10.1.2 Atrial Septal Defect Repair

2.2.10.1.3 Ventricular Septal Defect Repair

2.2.10.1.4 Patent Foramen Ovale Repair

2.2.10.2 Procedure Volumes Forecast

2.2.11 Vascular Access Site Closure

2.2.11.1 Vascular Access Site Closure Techniques

2.2.11.2 Procedure Volumes Forecast

2.2.12 Vulnerable Plaque Management

2.2.13 Emerging Approaches to Plaque Management

2.2.13.1 Cryoplasty

2.2.13.2 Systemic Biotherapies under Development for the Treatment of Arterial Atherosclerosis/Inflammation

2.2.13.3 Endovascular Phototherapy

Exhibit 2-1: Coronary Angiography, Procedure Volumes Forecast, 2004-2009

Exhibit 2-2: Intravascular Ultrasound, Procedure Volumes Forecast, 2004-2009

Exhibit 2-3: Functional Angiometry, Procedure Volumes Forecast, 2004-2009

Exhibit 2-4: Intracardiac Ultrasound, Procedure Volumes Forecast, 2004-2009

Exhibit 2-5: Percutaneous Transluminal Coronary Angioplasty, Caseload Forecast, 2004-2009

Exhibit 2-6: Coronary Stenting, Caseload Forecast, 2004-2009

Exhibit 2-7: Bare-Metal Coronary Stenting, Stent Placement Forecast, 2004-2009

Exhibit 2-8: Drug-Eluting Stents, Selected Follow-Up Data from Pivotal Clinical Trials

Exhibit 2-9: Drug-Eluting Coronary Stenting, Stent Placement Forecast, 2004-2009

Exhibit 2-10: Bare-Metal Stenting with Adjuvant Anti-Restenosis Drug Therapy, Caseload Forecast, 2004-2009

Exhibit 2-11: Coronary Mechanical Thrombectomy, Procedure Volumes Forecast, 2004-2009

Exhibit 2-12: Coronary Endovascular Brachytherapy, Procedure Volumes Forecast, 2004-2009

Exhibit 2-13: Coronary Mechanical Atherectomy, Procedure Volumes Forecast, 2004-2009

Exhibit 2-14: Coronary Laser Atherectomy, Procedure Volumes Forecast, 2004-2009

Exhibit 2-15: Coronary Mechanical Chronic Total Occlusion Crossing, Procedure Volumes Forecast, 2004-2009

Exhibit 2-16: Embolic Protection in Patients Undergoing Percutaneous Coronary Interventions and Saphenous Vein Grafting, Procedure Volumes Forecast, 2004-2009

Exhibit 2-17: Percutaneous Balloon Valvuloplasty, Procedure Volumes Forecast, 2004-2009

Exhibit 2-18: Transcatheter Septal Defect Repairs, Procedure Volumes Forecast, 2004-2009

Exhibit 2-19: Vascular Access Site Closure, Procedure Volumes Forecast, 2004-2009

Exhibit 2-20: 2005, Selected Systemic Biotherapies under Development for the Treatment of Arterial Atherosclerosis/Inflammation

3. INTERVENTIONAL CARDIOLOGY PRODUCTS MARKET

3.1 Diagnostic Interventional Cardiology Products

3.1.1 Coronary Angiography Devices

3.1.1.1 Types of Devices

3.1.1.1.1 Angiography Catheters

3.1.1.1.2 Diagnostic Guidewires

3.1.1.1.3 Sheaths

3.1.1.1.4 Angiography Accessories

3.1.1.2 Products

3.1.1.3 Market Forecast

3.1.1.4 Competitive Analysis

3.1.2 Intravascular Ultrasound Systems

3.1.2.1 Products

3.1.2.2 Market Forecast

3.1.2.3 Competitive Analysis

3.1.3 Functional Angiometry Wires

3.1.3.1 Products

3.1.3.2 Market Forecast

3.1.4 Intracardiac Ultrasound Systems

3.1.4.1 Products

3.1.4.2 Market Forecast

3.1.4.3 Competitive Analysis

3.2 Therapeutic Interventional Cardiology Products

3.2.1 Percutaneous Transluminal Coronary Angioplasty Products

3.2.1.1 Types of Devices

3.2.1.1.1 Balloon Catheters

3.2.1.1.2 Guiding Catheters

3.2.1.1.3 Therapeutic Guidewires

3.2.1.1.4 Introducers/Sheaths

3.2.1.1.5 Inflation Devices

3.2.1.2 Market Forecast

3.2.1.3 Competitive Analysis

3.2.2 Coronary Stenting Systems

3.2.2.1 Products

3.2.2.1.1 Bare-Metal Coronary Stent Products

3.2.2.1.2 Drug-Eluting Coronary Stent Products

3.2.2.1.2.1 Sirolimus-Eluting Stents/Stenting Systems

3.2.2.1.2.2 Paclitaxel-Eluting Stents/Stenting Systems

3.2.2.1.2.3 Everolimus-Eluting Stents/Stenting Systems

3.2.2.1.2.4 ABT-578-Eluting Stents/Stenting Systems

3.2.2.1.2.5 AP23573-Eluting Stents/Stenting Systems

3.2.2.1.2.6 Tacrolimus-Eluting Stents/Stenting Systems

3.2.2.1.2.7 Biolimus A9-Eluting Stents/Stenting Systems

3.2.2.1.2.8 Other Coronary Stents/Stenting Systems

3.2.2.2 Market Forecast

3.2.2.3 Competitive Analysis

3.2.3 Mechanical Thrombectomy Systems

3.2.3.1 Products

3.2.3.2 Market Forecast

3.2.4 Endovascular Brachytherapy Systems

3.2.4.1 Products

3.2.4.2 Market Forecast

3.2.5 Mechanical Atherectomy Systems

3.2.5.1 Products

3.2.5.2 Market Forecast

3.2.5.3 Competitive Analysis

3.2.6 Laser Atherectomy Systems

3.2.6.1 Products

3.2.6.2 Market Forecast

3.2.7 Chronic Total Occlusion Crossing Systems

3.2.7.1 Products

3.2.7.2 Market Forecast

3.2.7.3 Competitive Analysis

3.2.8 Embolic Protection Systems

3.2.8.1 Products

3.2.8.2 Market Forecast

3.2.8.3 Competitive Analysis

3.2.9 Percutaneous Balloon Valvuloplasty Systems

3.2.9.1 Products

3.2.9.2 Market Forecast

3.2.9.3 Competitive Analysis

3.2.10 Transcatheter Septal Defect Repair Systems

3.2.10.1 Products

3.2.10.2 Market Forecast

3.2.10.3 Competitive Analysis

3.2.11 Vascular Access Site Closure Systems

3.2.11.1 Products

3.2.11.2 Market Forecast

3.2.11.3 Competitive Analysis

Exhibit 3-1: Diagnostic and Therapeutic Interventional Cardiology, Procedure Volumes Forecast, 2004-2009

Exhibit 3-2: Diagnostic and Therapeutic Interventional Cardiology Products, Market Forecast, 2004-2009

Exhibit 3-3: Diagnostic Interventional Cardiology, Procedure Volumes Forecast, 2004-2009

Exhibit 3-4: Diagnostic Interventional Cardiology Products, Market Forecast, 2004-2009

Exhibit 3-5: Coronary Angiography, Average Transcatheter Device Usage

Exhibit 3-6: 2005, Selected Coronary Angiography Catheters

Exhibit 3-7: Coronary Angiography Devices, Market Forecast, 2004-2009

Exhibit 3-8: 2004, Coronary Angiography Devices Market, Share by Supplier

Exhibit 3-9: 2005, Selected Coronary Intravascular Ultrasound Catheter Products

Exhibit 3-10: Coronary Intravascular Ultrasound Catheter Products, Market Forecast, 2004-2009

Exhibit 3-11: 2004, Coronary Intravascular Ultrasound Catheter Products Market, Share by Supplier

Exhibit 3-12: 2005, Selected Functional Angiometry Wires

Exhibit 3-13: Functional Angiometry Wires, Market Forecast, 2004-2009

Exhibit 3-14: 2005, Selected Intracardiac Ultrasound Catheter Products

Exhibit 3-15: Intracardiac Ultrasound Catheter Products, Market Forecast, 2004-2009

Exhibit 3-16: 2004, Intracardiac Ultrasound Catheter Products, Share by Supplier

Exhibit 3-17: Therapeutic Interventional Cardiology, Procedure Volumes Forecast, 2004-2009

Exhibit 3-18: Therapeutic Interventional Cardiology Products, Market Forecast, 2004-2009

Exhibit 3-19: Percutaneous Transluminal Coronary Angioplasty, Average Transcatheter Device Usage

Exhibit 3-20: 2005, Selected Percutaneous Transluminal Coronary Angioplasty Balloon Catheters

Exhibit 3-21: 2005, Selected Coronary Guiding Catheters

Exhibit 3-22: 2005, Selected Coronary Guidewires for Therapeutic Procedures

Exhibit 3-23: 2005, Selected Introducers/Sheaths

Exhibit 3-24: 2005, Selected Inflation Devices

Exhibit 3-25: Percutaneous Transluminal Coronary Angioplasty Devices, Market Forecast, 2004-2009

Exhibit 3-26: 2004, Percutaneous Transluminal Coronary Angioplasty Devices Market, Share by Supplier

Exhibit 3-27: 2005, Selected Coronary Stents/Stenting Systems

Exhibit 3-28: Coronary Stents/Stenting Systems, Market Forecast, 2004-2009

Exhibit 3-29: 2004, Coronary Stents/Stenting Systems, Share by Supplier

Exhibit 3-30: Coronary Mechanical Thrombectomy Devices, Market Forecast, 2004-2009

Exhibit 3-31: Coronary Endovascular Brachytherapy Products, Market Forecast, 2004-2009

Exhibit 3-32: 2005, Selected Coronary Mechanical Atherectomy Systems

Exhibit 3-33: Coronary Mechanical Atherectomy Systems, Market Forecast, 2004-2009

Exhibit 3-34: 2004, Coronary Mechanical Atherectomy Systems, Share by Supplier

Exhibit 3-35: Coronary Laser Atherectomy Devices, Market Forecast, 2004-2009

Exhibit 3-36: 2005, Selected Chronic Total Occlusion Crossing Systems

Exhibit 3-37: Coronary Mechanical Chronic Total Occlusion Crossing Systems, Market Forecast, 2004-2009

Exhibit 3-38: 2004, Coronary Mechanical Chronic Total Occlusion Crossing Systems, Share by Supplier

Exhibit 3-39: 2005, Selected Coronary Embolic Protection Systems

Exhibit 3-40: Coronary Embolic Protection Systems, Market Forecast, 2004-2009

Exhibit 3-41: 2004, Embolic Protection Systems Market, Share by Supplier

Exhibit 3-42: 2005, Selected Percutaneous Balloon Valvuloplasty Systems

Exhibit 3-43: Percutaneous Balloon Valvuloplasty Systems, Market Forecast, 2004-2009

Exhibit 3-44: 2004, Percutaneous Balloon Valvuloplasty Systems Market, Share by Supplier

Exhibit 3-45: 2005, Selected Transcatheter Septal Defect Repair Systems

Exhibit 3-46: Transcatheter Septal Defect Repair Devices, Market Forecast, 2004-2009

Exhibit 3-47: 2004, Transcatheter Septal Defect Repair Devices Market, Share by Supplier

Exhibit 3-48: 2005, Selected Vascular Access Site Closure Systems

Exhibit 3-49: Vascular Access Site Closure Systems, Market Forecast, 2004-2009

Exhibit 3-50: 2004, Vascular Access Site Closure Systems Market, Share by Supplier

4. COMPANY PROFILES

4.1 Abbott Laboratories

4.2 AGA Medical Corporation

4.3 B. Braun Melsungen AG

4.4 Boston Scientific Corporation

4.5 Cordis Corporation/Johnson & Johnson

4.6 EPMedSystems, Inc.

4.7 Guidant Corporation

4.8 IntraLuminal Therapeutics, Inc.

4.9 LuMend, Inc./Johnson & Johnson

4.10 Medtronic, Inc.

4.11 NMT Medical, Inc.

4.12 Possis Medical, Inc.

4.13 Siemens Medical Solutions, Inc./Siemens AG

4.14 Spectranetics Corporation

4.15 St. Jude Medical, Inc.

4.16 Toray Medical Co., LTD/Toray Industries, Inc./Toray Group

4.17 Volcano Therapeutics, Inc.



COMPANIES COVERED:

  1. Abbott Laboratories
  2. Abbott Vascular Devices, Inc.
  3. Acuson Corporation
  4. Advanced Bio Prosthetic Surfaces LTD
  5. AGA Medical Corporation
  6. Allvivo Vascular, Inc.
  7. Angiotech Pharmaceuticals, Inc.
  8. ARIAD Pharmaceuticals, Inc.
  9. Arrow International, Inc.
  10. Asahi Intecc Company LTD
  11. Asahi Intecc, Inc.
  12. Astellas Pharma, Inc.
  13. AtheroGenics, Inc.
  14. AVANT Immunotherapeutics, Inc.
  15. AVI BioPharma, Inc.
  16. C.R. Bard, Inc.
  17. Best Medical International, Inc.
  18. Best Vascular, Inc.
  19. Biosensors International, Inc.
  20. Biosensors International PTE LTD
  21. BIOTRONIK
  22. Boston Scientific Corporation
  23. B. Braun Medical, Inc.
  24. B. Braun Melsungen AG
  25. Cardia, Inc.
  26. Carmeda AB
  27. Conor Medsystems, Inc.
  28. Cook Group, Inc.
  29. Cordis Corporation
  30. Datascope Corporation Devax, Inc.
  31. Endovasc, Inc.
  32. EPMedSystems, Inc.
  33. ev3, Inc.
  34. FlowCardia, Inc.
  35. GlaxoSmithKline PLC
  36. W. L. Gore & Associates, Inc.
  37. Guidant Corporation
  38. Guidewire Technologies, Inc.
  39. Implant Sciences Corporation
  40. InSitu Technologies, Inc.
  41. IntraLuminal Therapeutics, Inc.
  42. Invatec SRL
  43. Johnson & Johnson
  44. Kensey Nash Corporation
  45. Eli Lilly and Company
  46. Lipid Sciences, Inc.
  47. LuMend, Inc.
  48. Marine Polymer Technologies, Inc.
  49. Medinol LTD
  50. Medtronic, Inc.
  51. Merit Medical Systems, Inc.
  52. Miravant Medical Technologies
  53. MIV Therapeutics, Inc.
  54. NMT Medical, Inc.
  55. Novartis Pharma Corporation
  56. Novoste Corporation
  57. NuMED, Inc.
  58. OrbusNeich Company LTD
  59. Pfizer, Inc.
  60. Pharmacyclics, Inc.
  61. Possis Medical, Inc.
  62. REVA Medical, Inc.
  63. Rubicon Medical Corporation
  64. Sahajanand Medical Technologies PVT LTD
  65. Sakura Finetek Company LTD
  66. Sakura Finetek, Inc.
  67. sanofi-aventis
  68. Scion Cardio-Vascular, Inc.
  69. Siemens AG
  70. Siemens Medical Solutions, Inc.
  71. Sorin Biomedica Cardio SPA
  72. Spectranetics Corporation
  73. St. Jude Medical, Inc.
  74. SurModics, Inc.
  75. Sutura, Inc.
  76. Terumo Europe NV
  77. Terumo Medical Corporation
  78. Toray Industries, Inc.
  79. Toray, Inc.
  80. Translumina GmbH
  81. Vascular Solutions, Inc.
  82. Volcano Therapeutics, Inc.
  83. Wyeth Pharmaceuticals
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