U.S. MARKETS FOR CURRENT AND EMERGING WOUND CLOSURE TECHNOLOGIES

149 Pages | 40 Exhibits | 2012 Analysis | Forecasts Through 2016 Product Family: Market Reports




OVERVIEW:
In 2011, nearly 100 million wounds were treated in U.S. hospitals; these included amputations; arterial, diabetic, pressure, and venous ulcers; burns, surgical wounds; and traumatic wounds. In the same year, treatment of these wounds generated more than $3.8 billion in wound closure product sales (including traditional products such as sutures, stapling systems, and wound closure strips, as well as emerging products such as surgical sealants and glues, energy-based closure devices, automated suturing products, and negative pressure wound therapy systems). Over the forecast period covered by this report, sales of traditional and emerging wound closure products are expected to increase at a compound annual rate of 4.0%, reaching more than $4.6 billion in the year 2016.

This new report by Medtech Insight presents a detailed overview of the U.S. current and emerging wound closure products market. Major topics covered by this report include a an overview of the physiology of wound closure; a discussion of traditional wound closure products such as sutures, stapling products, and wound closure strips; a discussion of emerging wound closure products such as surgical sealants and glues, energy-based closure devices, automated suturing devices, and negative pressure wound therapy products; and analyses of the sales and leading competitors in each of these markets.

TABLE OF CONTENTS:
EXECUTIVE SUMMARY

i. Wound Closure 
ii. Wound Types 
iii. Traditional Wound Closure Products Market 
	a. Sutures 
	b. Surgical Stapling Products 
	c. Wound Closure Strips 
	d. Market Analysis 
iv. Emerging Wound Closure Products Market 
	a. Surgical Sealants and Glues 
	b. Energy-Based Wound Closure Products 
	c. Automated Suturing Devices 
	d. Negative Pressure Wound Therapy Products 
	e. Market Analysis 
v. Combined Market Forecast 

Exhibit ES-1: Phases of the Wound Closure Process 
Exhibit ES-2: 2009, Incidence of Major Wound Types 
Exhibit ES-3: Traditional Wound Closure Products, Market Forecast,  2011-2016 
Exhibit ES-4: Emerging Wound Closure Products, Market Forecast, 2011-2016 
Exhibit ES-5: Wound Closure Products, Combined Market Forecast, 2011-2016 

1. CLINICAL ISSUES IN WOUND MANAGEMENT

1.1 Physiology of Wound Closure 
	1.1.1 Layers of the Skin and Supporting Structures 
		1.1.1.1 Epidermis 
		1.1.1.2 Dermis 
		1.1.1.3 Hypodermis 
		1.1.1.4 Fascia 
		1.1.1.5 Muscle 
		1.1.1.6 Bone 
	1.1.2 Wound Closure Process 
		1.1.2.1 Hemostasis 
		1.1.2.2 Inflammation 
		1.1.2.3 Proliferation 
		1.1.2.4 Remodeling Phase 
1.2 Factors Affecting Wound Closure 
	1.2.1 Intrinsic Factors 
		1.2.1.1 Age and Chronic Illness 
		1.2.1.2 Body Composition 
		1.2.1.3 Nutritional Status 
	1.2.2 Extrinsic Factors 
		1.2.2.1 Ambient Temperature 
		1.2.2.2 Desiccation/Hydration 
		1.2.2.3 Infection 
		1.2.2.4 Maceration 
		1.2.2.5 Medication and Other Treatment Modalities 
		1.2.2.6 Necrotic Tissue and Debris 
		1.2.2.7 Oxygen 
		1.2.2.8 Stress 
		1.2.2.9 Wound Creation and Depth 
		1.2.2.10 Wound Closure Techniques
		1.2.2.11 Other Extrinsic Factors 
	1.2.3 Complications of Wound Healing 
		1.2.3.1 Scarring 
		1.2.3.2 Bleeding 
1.3 Wound Types 
	1.3.1 Illness-Related Wounds 
		1.3.1.1 Etiology 
			1.3.1.1.1 Arterial Ulcers 
			1.3.1.1.2 Diabetic Ulcers 
			1.3.1.1.3 Venous Ulcers 
		1.3.1.2 Epidemiology 
	1.3.2 Pressure Ulcers 
		1.3.2.1 Etiology 
		1.3.2.2 Epidemiology 
	1.3.3 Surgical Wounds 
		1.3.3.1 Etiology 
		1.3.3.2 Epidemiology 
	1.3.4 Traumatic Wounds 
		1.3.4.1 Etiology 
			1.3.4.1.1 Abrasions, Contusions,and Lacerations 
			1.3.4.1.2 Amputations 
			1.3.4.1.3 Burns 
		1.3.4.2 Epidemiology 

Exhibit 1-1: The Skin's Layers and Supporting Structures 
Exhibit 1-2: Phases of the Wound Closure Process 
Exhibit 1-3: Intrinsic and Extrinsic Factors Affecting Wound Closure 
Exhibit 1-4: Illness-Related Wounds, Facts and Figures, 1996-2006, and 2009 
Exhibit 1-5: Pressure Ulcers, Facts and Figures, 1996-2006, and 2009 
Exhibit 1-6: Stages of Pressure Ulcers 
Exhibit 1-7: Surgical Wounds, Facts and Figures, 1996-2006, and 2009 
Exhibit 1-8: Lacerations and Other Types of Traumatic Wounds,  Facts and Figures, 1996-2006, and 2009 
Exhibit 1-9: Amputations, Facts and Figures, 1996-2006, and 2009 
Exhibit 1-10: Burns, Facts and Figures, 1996-2006, and 2009 
Exhibit 1-11: Classification of Burns, by Mechanism of Injury 
Exhibit 1-12: Classification of Burns, by Extent of Injury 

2. TRADITIONAL WOUND CLOSURE PRODUCTS MARKET

2.1 Sutures 
	2.1.1 Types 
		2.1.1.1 Monofilament and Multifilament 
		2.1.1.2 Nonresorbable 
		2.1.1.3 Resorbable 
		2.1.1.4 Antimicrobial 
	2.1.2 Products 
	2.1.3 Market Analysis 
	2.1.4 Competitive Analysis 
2.2 Stapling Products 
	2.2.1 Types 
	2.2.2 Products 
	2.2.3 Market Analysis 
	2.2.4 Competitive Analysis 
2.3 Wound Closure Strips 
	2.3.1 Products 
	2.3.2 Market Analysis 
	2.3.3 Competitive Analysis 
2.4 Combined Market Analysis 

Exhibit 2-1: Sutures, Market Forecast, 2011-2016 
Exhibit 2-2: 2011, Sutures Market, Share by Supplier 
Exhibit 2-3: Surgical Stapling Products, Market Forecast, 2011-2016 
Exhibit 2-4: 2011, Surgical Stapling Products Market, Share by Supplier 
Exhibit 2-5: Wound Closure Strips, Market Forecast, 2011-2016 
Exhibit 2-6: 2011, Wound Closure Strips Market, Share by Supplier 
Exhibit 2-7: Traditional Wound Closure Products, Combined Market Forecast, 2011-2016 

3. EMERGING WOUND CLOSURE PRODUCTS MARKET

3.1 Surgical Sealants and Glues 
	3.1.1 Applications 
		3.1.1.1 Cardiac and Vascular Surgery 
		3.1.1.2 General Surgery 
		3.1.1.3 Thoracic Surgery 
		3.1.1.4 Aesthetic and Otolaryngologic Surgery 
		3.1.1.5 Neurologic and Spine Surgery 
	3.1.2 Fibrin Sealants 
		3.1.2.1 Composition 
		3.1.2.2 Application Methods 
	3.1.3 Autologous-Processed Sealants 
	3.1.4 Collagen- and Albumin-Based Sealants 
	3.1.5 Cyanoacrylate-Based Sealants 
	3.1.6 Polymer-Based Sealants 
	3.1.7 Market Analysis 
	3.1.8 Competitive Analysis 
3.2 Energy-Based Wound Closure Products 
	3.2.1 Radiofrequency Closure 
		3.2.1.1 Monopolar/Bipolar 
	3.2.2 Ultrasonic Closure 
	3.2.3 Thermal Closure 
	3.2.4 Market Analysis 
	3.2.5 Competitive Analysis 
3.3 Automated Suturing Devices 
	3.3.1 Market Analysis 
	3.3.2 Competitive Analysis 
3.4 Negative Pressure Wound Therapy 
	3.4.1 Market Analysis 
	3.4.2 Competitive Analysis 
3.5 Combined Market Analysis 

Exhibit 3-1: Modes of Action for Surgical Sealants and Glues 
Exhibit 3-2: Comparison of Biologic and Synthetic Sealants 
Exhibit 3-3: Usage of Surgical Sealants and Glues, by Specialty 
Exhibit 3-4: Major Applications for Surgical Sealants and Glues in Cardiac and Vascular Surgery 
Exhibit 3-5: Major Applications for Surgical Sealants and Glues in General Surgery 
Exhibit 3-6: Major Applications for Surgical Sealants and Glues in Thoracic Surgery 
Exhibit 3-7: Surgical Sealants and Glues, Market Forecast, 2011-2016 
Exhibit 3-8: 2011, Surgical Sealants and Glues Market, Share by Supplier 
Exhibit 3-9: Effects of Temperature on Collagenous Tissue 
Exhibit 3-10: Energy-Based Wound Closure Devices,  Market Forecast, 2011-2016 
Exhibit 3-11: 2011, Energy-Based Wound Closure Devices Market,  Share by Supplier 
Exhibit 3-12: Automated Suturing Products, Market Forecast, 2011-2016 
Exhibit 3-13: 2011, Automated Suturing Products Market, Share by Supplier 
Exhibit 3-14: Negative Pressure Wound Therapy Products,  Market Forecast, 2011-2016 
Exhibit 3-15: 2011, Negative Pressure Wound Therapy Products Market, Share by Supplier 
Exhibit 3-16: Emerging Wound Closure Products, Combined Market Forecast, 2011-2016 

4. COMPANY PROFILES

4.1 3M Health Care/3M Company 
4.2 Baxter Healthcare Corporation/Baxter International, Inc. 
4.3 Covidien LTD 
4.4 CryoLife, Inc. 
4.5 Ethicon, Inc./Johnson & Johnson 
4.6 Kinetic Concepts, Inc. 
4.7 Olympus America, Inc./Olympus Corporation 

APPENDIX:  COMPANY LISTING 



COMPANIES COVERED:

  1. 3M Health Care/3M Company
  2. Advanced Medical Solutions PLC
  3. Aesculap, Inc./B. Braun Melsungen AG
  4. Angiotech Pharmaceuticals, Inc.
  5. ArthroCare Corporation
  6. Asahi Kasei Medical Co., LTD
  7. Autosuture/Covidien LTD
  8. Baxter Healthcare Corporation/ Baxter International, Inc.
  9. B. Braun Melsungen AG
  10. Biomet Biologics, Inc./Biomet, Inc.
  11. Cascade Medical Enterprises LLC
  12. Closure Medical Corporation/Ethicon/Johnson & Johnson
  13. Cohera Medical, Inc.
  14. ConMed Corporation
  15. Covalent Medical, Inc.
  16. Covidien LTD
  17. CryoLife, Inc.
  18. CSL Behring, Inc./CSL LTD
  19. Cytomedix, Inc.
  20. DemeTECH, Inc.
  21. Derma Sciences, Inc.
  22. DeRoyal Industries, Inc.
  23. Dynarex Corporation
  24. EndoGastric Solutions Inc.
  25. Ethicon/Johnson & Johnson
  26. Ethicon Endo-Surgery/Johnson & Johnson
  27. GEM SRL
  28. W.L. Gore & Associates, Inc.
  29. Grams Suture Corporation
  30. Gyrus ACMI/Olympus America, Inc./Olympus Corporation
  31. Harvest Technologies Corporation
  32. Henkel Corporation
  33. Incisive Surgical, Inc.
  34. Innovative Therapies, Inc.
  35. Kendall/Covidien LTD
  36. Kimberly Clark Corporation
  37. Kinetic Concepts, Inc.
  38. Kuros Biosurgery AG
  39. LSI Solutions, Inc.
  40. Medela, Inc.
  41. Medline Industries, Inc.
  42. Medtronic, Inc.
  43. Microline Surgical, Inc./HOYA Corporation
  44. Olympus America, Inc./Olympus Corporation
  45. OMRIX biopharmaceuticals/Ethicon/Johnson & Johnson
  46. PARE Surgical, Inc.
  47. Salient Surgical Technologies, Inc./Medtronic Advanced Energy, Inc./ Medtronic, Inc.
  48. Smith & Nephew PLC
  49. Snowden-Pencer, Inc./CareFusion, Inc.
  50. SuturTek Incorporated
  51. Syneture/Covidien LTD
  52. Teleflex Medical/Teleflex, Inc.
  53. TissueSeal LLC
  54. Tornier, Inc.
  55. USGI Medical, Inc.
  56. Valleylab/Covidien LTD
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